The brain-computer interface enables direct communication between humans and machines through brain activity. It allows individuals with disabilities to control electric aids or prosthetics using their thoughts to perform necessary actions and convey messages. Furthermore, it interprets brain states and provides cognitive information required for applications. After decades of development, many applications of brain-computer interfaces have transitioned from science fiction to reality, attracting industrial investment in research and development. However, translating brain-computer interface technology into daily life still faces many limitations and challenges. This talk will provide an overview of the development of brain-computer interfaces in healthcare applications and discuss recent research on overcoming various challenges.